| Samstag, 17.09.2022 18:00 | |||||
| SG Ohlsbach/Elgersweier 2 - HSG Hanauerland 2 | 29:33 | (15:17) | |||
| Sonntag, 25.09.2022 15:00 | |||||
| HSG Hanauerland 2 - HTV Meißenheim 2 | 41:40 | (20:19) | |||
| Samstag, 01.10.2022 20:00 | |||||
| HSG Hanauerland 2 - TuS Altenheim 2 | 32:32 | (13:13) | |||
| Samstag, 22.10.2022 20:00 | |||||
| SG Hornberg/Lauterbach/Triberg - HSG Hanauerland 2 | 31:20 | (15:6) | |||
| Samstag, 29.10.2022 18:00 | |||||
| HSG Hanauerland 2 - HGW Hofweier 2 | 23:33 | (12:16) | |||
| Samstag, 05.11.2022 20:00 | |||||
| TuS Schutterwald 3 - HSG Hanauerland 2 | 40:22 | (18:12) | |||
| Samstag, 12.11.2022 17:30 | |||||
| HSG Hanauerland 2 - HSG Ortenau Süd 2 | 36:23 | (20:12) | |||
| Freitag, 25.11.2022 20:30 | |||||
| HSG Hanauerland 2 - SG Scutro 2 | 30:31 | (12:16) | |||
| Samstag, 10.12.2022 17:45 | |||||
| HSG Hanauerland 2 - ETSV Offenburg | 36:32 | (14:14) | |||
| Samstag, 17.12.2022 19:00 | |||||
| TuS Oppenau - HSG Hanauerland 2 | 34:25 | (15:9) | |||
| Samstag, 14.01.2023 16:00 | |||||
| HSG Hanauerland 2 - SG Ohlsbach/Elgersweier 2 | 27:31 | (14:13) | |||
| Samstag, 21.01.2023 18:00 | |||||
| HTV Meißenheim 2 - HSG Hanauerland 2 | 23:27 | (9:11) | |||
| Freitag, 27.01.2023 20:30 | |||||
| TuS Altenheim 2 - HSG Hanauerland 2 | 32:24 | (19:11) | |||
| Samstag, 04.03.2023 18:00 | |||||
| HSG Hanauerland 2 - SG Hornberg/Lauterbach/Triberg | 16:21 | (8:10) | |||
| Samstag, 11.03.2023 17:30 | |||||
| HGW Hofweier 2 - HSG Hanauerland 2 | 37:23 | (19:9) | |||
| Samstag, 18.03.2023 16:00 | |||||
| HSG Hanauerland 2 - TuS Schutterwald 3 | 23:24 | (12:11) | |||
| Samstag, 25.03.2023 18:00 | |||||
| HSG Ortenau Süd 2 - HSG Hanauerland 2 | 20:22 | (13:12) | |||
| Samstag, 15.04.2023 18:00 | |||||
| SG Scutro 2 - HSG Hanauerland 2 | 34:26 | (15:12) | |||
| Samstag, 22.04.2023 18:00 | |||||
| HSG Hanauerland 2 - TuS Oppenau | 25:26 | (16:14) | |||
| Samstag, 29.04.2023 18:00 | |||||
| ETSV Offenburg - HSG Hanauerland 2 | 16:32 | (10:16) | |||